Suplasyn is a sterile solution of highly purified sodium hyaluronate (Na-HA or"hyaluronan"). It is produced by bio-fermentation, thereby minimizing the risk of cross-species contamination or allergy to foreign proteins. Suplasyn is sterilized by aseptic filtration. Suplasyn is available in over 30 countries and benefits from an experience of over 10 years and millions of doses.
The treatment may consist of a single use (SUPLASYN 1-Shot, for large joints) or repeated doses, usually 3, at weekly intervals (SUPLASYN and SUPLASYN m.d.). Your physician will decide if additional doses could be of benefit. While symptoms may subside rapidly, the full benefits of the treatment are usually felt a few weeks after its completion. The majority of patients experience pain relief and joint function improvement, lasting approximately 6 months, up to 12 months. This depends on the condition of the individual patient and the severity of the disease. Once the beneficial effects of a course of SUPLASYN wear off, it is possible and safe to repeat the doses. Ask your physician for advice. Rest is recommended in the 48 hours following each use and strenuous activity should be avoided during the full course of the treatment.
Possible side effects
As with any intra-articular use, there may be a mild and short-lasting discomfort during the actual procedure. Following the use, some patients may experience a mild local reaction like pain, feeling of heat, redness and swelling. Usually, these symptoms disappear quickly (within a few days) and without any consequence. If these symptoms occur, rest and apply ice locally. If you feel that symptoms are severe or if they persist you should consult your physician. Do so immediately if you have fever following the use.
Suplasyn is marked in the EU as a Medical Device and, as such, is not considered as a drug. It contains hyaluronan, a substance that is naturally present in your joint. Suplasyn acts locally, directly within the affected joint and causes none of the gastrointestinal side effects associated with NSAIDs and analgesics.